Uveitis (inflammation of the middle layer of the eye)
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When treated with Wobenzym® PS (Phlogenzym), 60% of
patients with anterior uveitis were improved within about 17
days. I believe this data can be used to treat posterior
uveitis based on the ability of Wobenzym to decrease
TNF-alpha levels (a pro-inflammatory cytokine), and the
current trend to use anti-TNF alpha antibodies to treat
posterior uveitis. Wobenzym® has shown some effectiveness in treating Behcet's Disease, in which uveitis is a common presentation. Behcet’s may cause either anterior uveitis (inflammation in the front of the eye) or posterior uveitis (inflammation in the back of the eye), and sometimes causes both at the same time. Anterior uveitis results in pain, blurry vision, light sensitivity, tearing, or redness of the eye. Posterior uveitis may be more dangerous and vision–threatening because it often causes fewer symptoms while damaging a crucial part of the eye — the retina. From FREQUENTLY ASKED QUESTIONS, with answers by Joseph J Collins, RN, ND Read the special section: EYES, EARS, NOSE & THROAT CONDITIONS & WOBENZYM® |
What the literature says about Systemic Enzyme Support and:
When treated with Wobenzym® PS (Phlogenzyum),
60% of patients with anterior uveitis were improved within
about 17 days. I believe this data can be used to treat posterior
uveitis based on the ability of Wobenzym to decrease TNF-alpha
levels (a pro-inflammatory cytokine), and the current trend to use
anti-TNF alpha antibodies to treat posterior uveitis.
It should also be noted that Wobenzym has shown some effectiveness
in treating
Behcet's Disease, in which uveitis is a presentation.
Our
first experience with utilisation of hydrolytic enzymes in arterior
uveitis.
Porubská M. Department of
Ophthalmology, Institute of Respiratory Diseases, Nový Smokovec,
Slovakia. Rheumatologia 2000, Roč. 14, č. 2, str. 65-69.
(3-14-1)
Summary: Objective: New therapeutic methods
with lower adverse effects than those of corticosteroids and
immunosuppressive are seeked for in the treatment of anterior
uveitis. The aim of the monitoring was assess the efficacy of
Wobenzym and Phlogenzym in the anterior uveitis activity and to
compare their therapeutic effect with the effect of high doses of
both the system and parabulbar application of corticosteroids and/or
immunosuppressives.Methods: A group of 29 hospitalized patients with
the high activity of anterior acute and chronic uveitis received
enzyme preparations for 8 weeks and paralelly, decrease of
inflammatory activity was evaluated.Results: In a group of patients
with anterior acute uveitis mostly associated with ankylosing
spondylitis, inflammatory cells from the eye anterior chamber in
patients treated with hydrolytic enzymes got absorbed on average in
20 days compared to 27 days in the control group. In the patients
with chronic anterior uveitis mostly associated with juvenile
chronic arthritis all the inflammatory cells in 50 % of the patients
treated with Wobenzym got absorbed on average in 20.3 days, in 60
% of the patients treated with Phlogenzym they got absorbed on
average in 17.3 days with the most persisting effect and in the
control group in 37 % of 'the patients on average in 30 days. In the
patients receiving enzymes. Fibrín and Tyndal got absorbed in 1 day,
in the control group in 4-5 days.Conclusion: The results suggest
that, utilization of hydrolytic enzymes makes possible to lower the
dosage of corticoids and contributes to shorter time needed for
inhibition of the uveitis inflammatory activity, important
especially in children with JCA. The best results were observed
in administration of Phlogenzym.
Key words: hydrolytic enzymes, corticosteroids, anterior chamber,
uveitis.