Frequently Asked Questions
KIDNEY AND BLADDER CONDITIONS & WOBENZYM®
How can Wobenzym decrease the risk of developing
kidney stones?
In the most severe cases of
kidney stones - patients that need
surgical intervention to remove the stones – taking the systemic
enzymes made them significantly less likely to get stones again.
Now what is interesting is that in those studies, the patients took
enzymes for only four to five weeks – but they still had less risk
of developing new kidney stones a year later!!
From what I have been able to find in the literature, I would say
that by decreasing inflammation (and decreasing pro-inflammatory
cytokines such as IL-6 – which is associated with kidney stone
formation) , and pro-Wobenzym is able to inhibit the development of
kidney stones decrease the inflammatory.
But more than that, the enzymes in Wobenzym have proteolytic
properties may decrease formation of the organic (protein) component
of the kidney stone. In addition, the enzymes appear to be
interacting with bikunin, a glycoprotein that is a member of the
inter-alpha-trypsin inhibitor (ITI) family. Like
alpha-2-macroglobulin, the ITI family of glycoproteins modulate
inflammation. Proper function of bikunin decreases calcium oxylate
stone formation.
We also note that patients with kidney stones complicated by
pyelonephritis have very high levels of SIgA (secretory IgA) an
immunoglobulin involved in local immunity of mucus membranes. This
increase in the urine level of SIgA in patients with kidneys stones
and pyelonephritis can play apart in the development of kidney
stones. By normalizing urinary system local immunity, Wobenzym can
decreases kidney stone formation. So, there are a number of
mechanisms by which Woebnzym-N can decrease
kidney stone formation.
How
are kidney infections improved by using Wobenzym®?
In a study of 66 patients with chronic
pyelonephritis, Wobenzym yielded results that “considerably
exceeded those in conventional drug treatment.” This was evidenced
by both clinical findings (symptoms) as well as laboratory findings.
One reason for the notable benefit would be due to the normalization
of urinary system local immunity, as we just discussed.
Now I will be the first to admit that kidney infections are serious
conditions, and antibiotic therapy is very appropriate therapy. But
what we have observed is that chronic and recurrent infections –
infections that are resistant to improvement even on antibiotics –
do much better – and can be resolved when Wobenzym is added to the
treatment plan. Other conditions that are often resistance to
antibiotic therapy and benefit from this systemic enzyme therapy
also include and recurrent urinary tract infections, a very common
problem of the urinary system.
Is
Wobenzym useful for treating urinary tract infections?
Adding enzyme therapy to the antibiotic therapy
dramatically shortens the time that it takes both feel better, and
for lab tests to show a decrease in the systemic inflammation that
accompanies a
urinary tract infection.
This has been observed in the recurrent urinary tract infections –
which have traditionally been very hard to treat –even with
antibiotics and other drugs.
Keep in mind, these recurrent urinary tract infections are notorious
for being hard to treat and hard to keep coming back. The fact that
we can use Wobenzym to make antibiotics more effective – and to
prevent re-infection – is a very important point.
When we use Wobenzym to make antibiotic more effective we are using
the adjuvant properties of Wobenzym. An adjuvant is a substance that
significantly improves the effective of other therapies that have
limited effectiveness. Wobenzym has been used as an adjuvant to
treat a number of inflammatory and infectious diseases. This hold
true for not only
recurrent urinary tract infections and
pyelonephritis, but also for recurrent respiratory tract infections,
as well as chronic infections of the reproductive system.
How
does Wobenzym® help glomerulonephritis?
The benefits of Wobenzym® in regards to the
treatment of
glomerulonephritis is due
to many beneficial actions of Wobenzym® including among other
actions, its antioxidant effect, its anti-inflammatory functions,
and its ability to restore normal lipid (fats) metabolism. One study
concludes that Wobenzym® is the drug of choice, decreasing the
velocity of kidney destructive processes. [
more ]
How
does Wobenzym® help with diabetic kidney disease?
We know that Wobenzym can increase levels of C-peptide in
autoimmune mediated diabetes, such as type 1 diabetes. In addition
to showing much insulin the pancreas can still make, C-peptide
decreases the progression so the common complications of diabetes,
including the
diabetic nephropathy.
We also note that systemic enzymes can decrease the formation of
“advanced glycation end products” (AGEs), which are associated with
diabetic nephropathy and other complications of diabetes.
IN addition, abnormal cytokines levels are normalized, including
transforming growth factor beta-1 (TGF-b1), and interleukin 6.
What we have come to realize, is that the complications of diabetes
are strongly mediated by the immune system. We see that controlling
blood sugar with insulin is not enough to prevent complications such
as diabetic nephropathy. The abnormal cytokine levels that occur
with diabetes can safely and effectively be normalized with
Wobenzym.
This normalization of immune function is why Wobenzym should also be
used in other kidney diseases such as kidney stones, frequent
urinary tract infections and pyelonephritis.
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