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Systemic enzyme therapy in the treatment of chronic salpingitis and infertility.

Ivaniyta L.I., Ivaniyta S.O., Kornatskaya A.G., Belis N.I., Kondratiyk. Systemic enzyme therapy in the treatment of chronic salpingitis and infertility. Farm. Zh. (Kiev) 1998, No. 2, pp. 89-92. Abstract in  Ukrainian., translation into Czech

 30 women, mean age 26.5 years, with chronic salpingitis and infertility were observed. 18 women suffered from primary infertility, 12 from secondary one. 21 patients were previously treated (antiinflammatory, hormonal therapy). 27 patients were diagnosed with unilateral salpingitis, 3 with bilateral one. Treatment started after activation of chronic inflammatory process. First, pyrogenal was administered, followed by antibacterial, anticandidous, desensibilization, and vitamin therapy. Together with antibiotics, Wobenzym was administered at the dose of 5 dragees 3 times a day for 10 days. Patients in the control group received the same therapy without Wobenzym.
Already after 5-6 days of Wobenzym treatment, an improvement of patients' condition was observed. Frequency and intensity of abdominal pain and in 86.4 % normalization of body temperature, appetite and intestinal function was seen. Positive changes of inflammatory signs were found after treatment - decreased infiltration, disappearance of pain on palpation. Positive status was verified also by blood parameters: leukocyte count decreased from 8.0 ± 0.3 x 109 to 6.3 ± 0.1 x 109. Sedimentation normalized and concentration of C-reactive protein decreased under Wobenzym treatment. Above described parameters did not change in the control group.
In 20 out of 22 patients, normalization of microflora was found. Impaired menstrual cycle normalized in 75 % patients.