Use of
Phlogenzym® in the treatment of secretory otitis in the
outpatient practice
Veldová Z., Martínková R., Maděrová S.
Use of Phlogenzym® in the treatment of secretory otitis
in the outpatient practice.
Audiocentrum Praha. 62.
Congress of the Czech Society of Otorhinolaryngology and Surgery of
Head and Neck, September 9-11, 1999, Hradec Králové, Czech Republic.
(17-01-2)
Chronic secretory otitis is a special
type of middle ear inflammation causing very often conductive
hearing loss, thus showing a negative influence on a speech
development in preschool children.
The authors present their first experience with the preparation
Phlogenzym in secretory otitis conservative treatment. Phlogenzym is
a combined enzyme preparation showing antiedematous, antiphlogistic,
fibrinolytic, and immunomodulatory effects.
26 children were included in the follow-up (group E - enzyme). They
received Phlogenzym in addition to the conventional treatment for 3
months. 16 patients receiving the same conventional treatment
previously formed a control retrospective group (group K).
Tympanometric curve was normalized completely in 60 % of patients of
the group E in comparison with 25 % of the group K. The threshold of
air conduction (conductive component oh hearing loss) was decreased
in the group E by 35 %, compared to 25 % in the group K. In the case
of failed conservative medicamentous treatment an operative
treatment was necessary only in 7.7 % of the group E patients in
comparison with 25 % of the group K. Moreover, the test of
phonematic hearing according to Škodová was evaluated in 12 children
of the group E. It showed a significant shift of perception of
distinctive speech sound features (voiced x voicedless). A positive
influence of therapy occurred in 83 % (of 12 children).
Thus, Phlogenzym appears as a suitable part of complex conservative
secretory otitis treatment, improving its efficiency.